Organ transplantation is a lifesaving procedure for end stage organ failure. Solid organ transplantation involves replacing the diseased or failing organ with a new, healthy one. Commonly transplanted organs are kidney, liver, heart and lung.

Successful solid organ transplantation requires suppression of the recipient’s immune system to ensure the transplanted organ is accepted and rejection is prevented. Patients usually require multi-drug immunosuppressive therapy, which is often initiated by an antibody medication.